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Nonprofits in South Carolina

What the IRS records say about tax-exempt organizations in South Carolina.

Tax-exempt organizations
32,595
Revenue in a year
$41.9 billion
on 8,916 e-filed returns
Assets
$72.3 billion
Employees
216,328
People paid $1 million or more
105
Typical top pay
$79,200
median, best-paid person per organization

South Carolina rankings

Tax-exempt organizations
32,595
Of which 501(c)(3)
28,746
File the 990-N (receipts ≤ $50,000)
16,796
File Form 990 or 990-EZ
7,447
Filed a 990-N (latest e-Postcard on record)
17,767
Exemption automatically revoked (all years)
14,592

Largest nonprofits in South Carolina by revenue

Top 5s in South Carolina

From each organization's latest e-filed Form 990, 990-EZ or 990-PF.

Highest-paid people

Compensation from the organization and related organizations, including other pay

  1. 1Charles David CerulloDirector / President & CEO · Inspirational Network Inc · INDIAN LAND, SC$5M
  2. 2Tod AugsburgerPresident and CEO · Lexington Health Inc · WEST COLUMBIA, SC$4.3M
  3. 3Mark S O'HallaPresident and CEO of Prisma Health · Prisma Health · GREENVILLE, SC$3.4M
  4. 4Elmer HolstienPresident/CEO · Apella Health Management Inc · SPARTANBURG, SC$2.7M
  5. 5Donna C IsgettPresident/CEO · McLeod Health · FLORENCE, SC$2.4M
The full top 10 →

Most raised in gifts and grants

Contributions, gifts and grants received in the year

  1. 1The Blackbaud Giving FundDANIEL ISLAND, SC · 990, year ended Dec 2025$544.3M
  2. 2Charter Institute at ErskineCOLUMBIA, SC · 990, year ended Jun 2025$294M
  3. 3Prisma Health-MidlandsGREENVILLE, SC · 990, year ended Sep 2025$151.2M
  4. 4Joy Unspeakable FoundationCHARLESTON, SC · 990-PF, year ended Dec 2024$150M
  5. 5The Medical University of South Carolina FoundationCHARLESTON, SC · 990, year ended Jun 2025$93.1M
The full top 10 →

Largest reserves

Net assets (fund balance) at year end

  1. 1McLeod Regional Medical Center of the Pee Dee IncFLORENCE, SC · 990, year ended Sep 2025$2.6B
  2. 2Prisma HealthGREENVILLE, SC · 990, year ended Sep 2025$2.4B
  3. 3Roper ST Francis HealthcareLADSON, SC · 990, year ended Dec 2024$1.8B
  4. 4Lexington Health IncWEST COLUMBIA, SC · 990, year ended Sep 2025$1.6B
  5. 5Furman UniversityGREENVILLE, SC · 990, year ended Jun 2025$1.2B
The full top 10 →

Biggest employers

Employees reported for the calendar year

  1. 1Prisma Health - UpstateGREENVILLE, SC · 990, year ended Sep 202512,204
  2. 2Apella Health Management IncSPARTANBURG, SC · 990, year ended Sep 20258,982
  3. 3Prisma Health-MidlandsGREENVILLE, SC · 990, year ended Sep 20258,246
  4. 4Roper ST Francis HealthcareLADSON, SC · 990, year ended Dec 20248,112
  5. 5Prisma HealthGREENVILLE, SC · 990, year ended Sep 20257,042
The full top 10 →

By city

By category

Category (NTEE)Organizations
Education2,300
Human services2,159
Religion-related1,390
Arts, culture and humanities1,185
Recreation and sports1,128
Philanthropy, voluntarism and grantmaking foundations1,005
Community improvement and capacity building969
Youth development685
Animal-related635
Public and societal benefit550
Health care513
Housing and shelter401
Mental health and crisis intervention322
Environment294
Food, agriculture and nutrition232
Public safety, disaster preparedness and relief230
Mutual and membership benefit192
Crime and legal-related190
International, foreign affairs and national security176
Voluntary health associations and medical disciplines158
Employment117
Civil rights, social action and advocacy99
Medical research73
Unknown65
Science and technology55
Social science14