Skip to main content
IRS-authorized e-file provider · not the IRS

Nonprofit · EIN 46-5727883

GRACE SCIENCE FOUNDATION

Tax-exempt · MENLO PARK, CA 94025

Financials

$827K$1.3M2023$943K$1.5M2024
Revenue Expenses · by fiscal year end
Financials of GRACE SCIENCE FOUNDATION by year, from its e-filed returns
Year endedFormRevenueExpensesNet incomeTotal assetsLiabilitiesNet assets
December 31, 2024990$943,011$1,519,386-$576,375$2,224,370$1,004$2,223,366
December 31, 2023990$826,626$1,289,174-$462,548$2,790,274$42,997$2,747,277
Financial details: 990 for the year ended December 31, 2024

Revenue

Contributions, gifts and grants
$869,699
Program service revenue
$0
Investment income
$73,312
Other revenue
$0

Expenses

Grants and similar amounts paid
$1,342,330
Compensation of officers, directors and key employees
$0
Salaries, compensation and benefits (total)
$0
Professional fundraising fees
$0
Legal fees
$779
Accounting fees
$17,420
Travel
$559
Program services (functional)
$1,391,084
Management and general (functional)
$128,302

Balance sheet and other

Total assets, start of year
$2,790,274
Total assets, end of year
$2,224,370
Total liabilities, end of year
$1,004
Net assets, end of year
$2,223,366
Gross receipts
$943,011
Employees
0
Volunteers
0
Year formed
2014
State of legal domicile
CA

From the e-filed returns the IRS publishes as XML (latest three processing years; amended returns replace the original). PDF copies at the IRS.

Officers, directors and key employees

As listed on the 990 for the year ended December 31, 2024, highest compensation first.

NameTitleHours / weekCompensation
Matthew WilseyPresident
Trustee or director, Officer
0$0
Egon DurbanChief Financial Officer
Trustee or director, Officer
0$0
KEN DRAZANSecretary
Trustee or director, Officer
0$0
Pete BrigerDirector
Trustee or director
0$0
Chelsea ClintonDirector
Trustee or director
0$0
J Taylor CrandallDirector
Trustee or director
0$0
Elle StephensDirector
Trustee or director
0$0
990 for the year ended December 31, 2023: 7 people
NameTitleHours / weekCompensation
Matthew WilseyPresident
Trustee or director, Officer
0$0
Egon DurbanChief Financial Officer
Trustee or director, Officer
0$0
KEN DRAZANSecretary
Trustee or director, Officer
0$0
Pete BrigerDirector
Trustee or director
0$0
Chelsea ClintonDirector
Trustee or director
0$0
J Taylor CrandallDirector
Trustee or director
0$0
Elle StephensDirector
Trustee or director
0$0

Address and contacts

Address (IRS master file)
873 SANTA CRUZ AVE STE 200, MENLO PARK, CA 94025-4635
In care of
% GRACE SCIENCE FOUNDATION
Principal officer (990 for 2024)
MATTHEW R WILSEY, 873 SANTA CRUZ AVENUE SUITE 2, MENLO PARK, CA 94025
Signed the 990
MATTHEW R WILSEY, PRESIDENT
Phone
(650) 746-4591
Return prepared by
WITHUMSMITHBROWNPC

California records

California keeps its own records of charities and corporations. Search them by EIN 46-5727883 or by the name GRACE SCIENCE FOUNDATION.

Attorney General, Registry of Charities and Fundraisers
Registration status and filed reports (CT-TR-1, RRF-1)

Mission

THE MISSION OF THE FOUNDATION IS TO SUPPORT AND FUND THE DEVELOPMENT OF LIFE-SAVING TREATMENT FOR PATIENTS THAT ARE DEFICIENT IN THE N-GLYCANESE ENZYME AND THOSE SUFFERING FROM RELATED GENETIC DISEASES. THE ACTIVITIES OF THE FOUNDATION WILL INVOLVE PROVIDING GRANT FUNDING TO HOSPITALS AND MEDICAL RESESARCH FACILITIES WHICH ARE CONDUCTING MEDICAL RESEARCH IN VARIOUS FIELDS RELATING TO THE SEARCH FOR UNDERSTNADING AND TREATMENT OF THIS CONDITION, FOSTERING COLLABORATION BETWEEN ACADEMIA, RESEARCH INSTITUTIONS, HOSPITALS, PRIVATE COMPANIES, AND GOVERNMENTAL AGENCIES.

990 for the year ended December 31, 2024

Program accomplishments

  • Baylor College of Medicine NGLY1 Natural History Study (Bernhard Suter) Team is conducting a natural history study to define the clinical spectrum of the disease and its progression, and define biomarker endpoints for use in therapeutic trials. This study is led by Dr. Bernhard Suter, MD, a child neurologist and medical geneticist. The study is collecting longitudinal measures of movement concurrently with clinical and biomarker measures to define aspects of gait and movement that are most affected in the disorder, characterize progression of the disease, select clinical features for performing longitudinal assessments, and inform clinical endpoint development for therapeutic trials.
    Expenses $452,697 · grants $452,697
  • Psychogenics Inc. Team has imported and is analyzing mouse and rat models of NGLY1 Deficiency for testing of candidate therapies. Team has conducted several studies using an NGLY1 knockout rat model to test phenotypic rescue using candidate small molecule therapies (both novel and approved drugs).
    Expenses $352,945 · grants $352,945
  • THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (YAN LAB) Team continues work generating and characterizing several mouse models of NGLY1 Deficiency, including models in which the gene is inactivated in certain tissues and conditionally after birth. These mouse models have allowed them to characterize neurological phenotypes including neuronal loss, neuropathological changes, inflammation, sensory and motor defects, and disease associated biomarkers, all of which are also observed in NGLY1 Deficiency patients These animal models provide a foundation for testing candidate therapies, including gene therapies and small molecule drugs. The team has also found that NGLY1 Deficiency in mice triggers a specific innate immune pathway mediated by the cGAS/STING pathway. Using genetic and pharmacological approaches, the team has uncovered three different targets that can be modulated to reduce disease associated phenotypes and improve survival.
    Expenses $203,574 · grants $203,574
  • The University of North Carolina (Hantman Lab)
    Expenses $80,637 · grants $80,637
  • Charles River Laboratories
    Expenses $68,025 · grants $68,025
  • Boston Children's Hospital (Yu Lab)
    Expenses $49,108 · grants $49,108
  • Hilltop Lab Animals Inc.
    Expenses $27,695 · grants $27,695
  • Albert Einstein College of Medicine (Kaushik Lab)
    Expenses $24,241 · grants $24,241
  • Purdue University (Rochet Lab)
    Expenses $23,869 · grants $23,869
  • Pharmaron, Inc
    Expenses $20,356 · grants $20,356
  • Universitry of Utah (Chow Lab)
    Expenses $19,321 · grants $19,321
  • Standford University
    Expenses $10,115 · grants $10,115
  • University of Houston
    Expenses $9,747 · grants $9,747
  • Bioagilytix Labs
    Expenses $19,000
  • Transnetyx
    Expenses $13,904
  • Wuxi Apptec
    Expenses $10,481
  • MedChem Express LLC
    Expenses $5,369

What it must file and when

IRS records say it files Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N. Its accounting year ends in December, so each return is due on the 15th day of the 5th month after that.

Tax yearYear endedDueIRS public records
2025December 31, 2025May 15, 2026Check at the IRS
2024December 31, 2024May 15, 2025990 on file
2023December 31, 2023May 15, 2024990 on file

IRS record

EIN
46-5727883
Tax-exempt status
501(c)(3): Charitable, religious, educational or scientific organization
Foundation status
Publicly supported organization (170(b)(1)(A)(vi))
Donations deductible (Pub 78)
Public charity, 50% deduction limit
Exempt since
2014
Accounting year ends
December
Files
Form 990 or 990-EZ
Category (NTEE)
Medical research (H99)
Assets (IRS master file)
$2,658,672
Income (IRS master file)
$1,336,731

Filing history

FormYear endedRevenueExpensesAssetsReturn
990December 2024$943,011$1,519,386$2,224,370XML
990December 2023$826,626$1,289,174$2,790,274XML
990December 2022$1,236,228$1,218,482$3,183,591IRS
990December 2021–––IRS
990December 2020–––IRS
990December 2018–––IRS

990-N: the IRS bulk file holds only the latest e-Postcard per organization; earlier years come from archived copies of that file since 2020 and can have gaps (the IRS e-Postcard search lists every one). 990, 990-EZ, 990-PF, 990-T: every e-filed return in the IRS e-file index since 2019; XML for the latest three processing years, amounts from the IRS Statistics of Income extracts before that. PDF copies and determination letters at the IRS (search EIN 46-5727883).

Questions about GRACE SCIENCE FOUNDATION

What is the EIN of GRACE SCIENCE FOUNDATION?
The employer identification number (EIN) of GRACE SCIENCE FOUNDATION is 46-5727883.
Is GRACE SCIENCE FOUNDATION tax-exempt?
Yes. The IRS lists it as tax-exempt under section 501(c)(3) since 2014.
Are donations to GRACE SCIENCE FOUNDATION tax-deductible?
Yes. It is listed in IRS Publication 78 (Public charity, 50% deduction limit).
Which annual return does GRACE SCIENCE FOUNDATION file?
Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N.
When is the next return of GRACE SCIENCE FOUNDATION due?
The return for tax year 2026 (the year ending December 31, 2026) is due May 17, 2027. Form 8868 extends it by six months; the 990-N cannot be extended.
When did GRACE SCIENCE FOUNDATION last file with the IRS?
The latest return in the IRS public files is the 990 for the year ended December 2024.
Who is the principal officer of GRACE SCIENCE FOUNDATION?
The 990 for the year ended December 31, 2024 names MATTHEW R WILSEY.
Who are the officers and directors of GRACE SCIENCE FOUNDATION?
The 990 for the year ended December 31, 2024 lists 7 people; 0 received compensation from the organization.
How much revenue does GRACE SCIENCE FOUNDATION have?
On its 990 for the year ended December 31, 2024 it reported revenue of $943,011, expenses of $1,519,386 and total assets of $2,224,370 at year end.

Other nonprofits in MENLO PARK

All nonprofits in MENLO PARK · California · Medical research