Nonprofit · EIN 46-4309387
USHER 1F COLLABORATIVE INC
Tax-exempt · NEWTONVILLE, MA 02460
Financials
| Year ended | Form | Revenue | Expenses | Net income | Total assets | Liabilities | Net assets |
|---|---|---|---|---|---|---|---|
| December 31, 2025 | 990 | $743,572 | $885,485 | -$141,913 | $691,312 | $55,407 | $635,905 |
| December 31, 2024 | 990 | $845,716 | $871,099 | -$25,383 | $781,549 | $3,731 | $777,818 |
| December 31, 2023 | 990 | $446,533 | $646,264 | -$199,731 | $810,900 | $7,699 | $803,201 |
Financial details: 990 for the year ended December 31, 2025
Revenue
- Contributions, gifts and grants
- $463,492
- Program service revenue
- $0
- Investment income
- $15,727
- Net income from fundraising events
- $263,661
- Other revenue
- $264,353
Expenses
- Grants and similar amounts paid
- $696,990
- Other salaries and wages
- $80,431
- Salaries, compensation and benefits (total)
- $88,971
- Professional fundraising fees
- $0
- Legal fees
- $1,150
- Accounting fees
- $9,555
- Travel
- $806
- Program services (functional)
- $712,836
- Management and general (functional)
- $37,032
- Fundraising (functional)
- $135,617
Balance sheet and other
- Total assets, start of year
- $781,549
- Total assets, end of year
- $691,312
- Total liabilities, end of year
- $55,407
- Net assets, end of year
- $635,905
- Net assets without donor restrictions
- $580,805
- Net assets with donor restrictions
- $55,100
- Gross receipts
- $826,632
- Employees
- 1
- Volunteers
- 25
- Year formed
- 2013
- State of legal domicile
- MA
From the e-filed returns the IRS publishes as XML (latest three processing years; amended returns replace the original). PDF copies at the IRS.
Officers, directors and key employees
As listed on the 990 for the year ended December 31, 2025, highest compensation first.
| Name | Title | Hours / week | Compensation |
|---|---|---|---|
| Melissa Chaikof | Chair and Trustee Trustee or director, Officer | 40 | $0 |
| Elliot Chaikof | Vice Chair and Trustee Trustee or director, Officer | 2 | $0 |
| Frank Gentile | Treasurer and Trustee Trustee or director, Officer | 2 | $0 |
| Jared Root | Secretary and Trustee Trustee or director, Officer | 4 | $0 |
| Joshua Cohen | Trustee Trustee or director | 2 | $0 |
| Rachel Root | Trustee Trustee or director | 2 | $0 |
| Julian Seewald | Trustee Trustee or director | 2 | $0 |
| Sari L Springer | Trustee Trustee or director | 2 | $0 |
| Heather Rosenstein | Trustee Trustee or director | 2 | $0 |
| Eric Halper | Trustee Trustee or director | 2 | $0 |
| Margi Levitt | Trustee Trustee or director | 2 | $0 |
| Dorie Shapiro | Trustee Trustee or director | 2 | $0 |
990 for the year ended December 31, 2024: 12 people
| Name | Title | Hours / week | Compensation |
|---|---|---|---|
| Joshua Cohen | Trustee Trustee or director | 2 | $0 |
| Rachel Root | Trustee Trustee or director | 2 | $0 |
| Julian Seewald | Trustee Trustee or director | 2 | $0 |
| Sari L Springer | Trustee Trustee or director | 2 | $0 |
| Heather Rosenstein | Trustee Trustee or director | 2 | $0 |
| Eric Halper | Trustee Trustee or director | 2 | $0 |
| Margi Levitt | Trustee Trustee or director | 2 | $0 |
| Dorie Shapiro | Trustee Trustee or director | 2 | $0 |
| Melissa Chaikof | Chair and Trustee Trustee or director, Officer | 40 | $0 |
| Elliot Chaikof | Vice Chair and Trustee Trustee or director, Officer | 2 | $0 |
| Frank Gentile | Treasurer and Trustee Trustee or director, Officer | 2 | $0 |
| Jared Root | Secretary and Trustee Trustee or director, Officer | 4 | $0 |
990 for the year ended December 31, 2023: 12 people
| Name | Title | Hours / week | Compensation |
|---|---|---|---|
| Sari L Springer | Trustee Trustee or director | 2 | $0 |
| Laurie Shapiro | Trustee Trustee or director | 2 | $0 |
| Julian Seewald | Trustee Trustee or director | 2 | $0 |
| Eric Halper | Trustee Trustee or director | 2 | $0 |
| Heather Rosenstein | Trustee Trustee or director | 2 | $0 |
| Lijun Sun | Trustee Trustee or director | 2 | $0 |
| Joshua Cohen | Trustee Trustee or director | 2 | $0 |
| Rachel Root | Trustee Trustee or director | 2 | $0 |
| Elliot Chaikof | Vice Chair and Trustee Trustee or director, Officer | 2 | $0 |
| Melissa Chaikof | Chair and Trustee Trustee or director, Officer | 40 | $0 |
| Jared Root | Secretary and Trustee Trustee or director, Officer | 2 | $0 |
| Frank Gentile | Treasurer and Trustee Trustee or director, Officer | 2 | $0 |
Address and contacts
- Address (IRS master file)
- 321 WALNUT ST 228, NEWTONVILLE, MA 02460-1927
- In care of
- % MELISSA CHAIKOF
- Mailing address (990-N for 2013)
- 165 Bigelow Rd, Newton MA 02465
- Principal officer (990 for 2025)
- Melissa Chaikof, 321 Walnut Street Ste 228, Newtonville, MA 02460
- Principal officer (990-N for 2013)
- Melissa Chaikof, 165 Bigelow Rd, Newton MA 02465
- Signed the 990
- MELISSA CHAIKOF, Chair and Trustee
- Phone
- (339) 221-2743
- Website
- http://usher1f.org
- Return prepared by
- Mullins PC
Mission
To fund medical research to find an effective treatment to save or restore the vision of those affected with Usher Syndrome Type 1F.
Program accomplishments
- 2025 Grants to Research Labs: Harvard Medical School, David Corey Lab: $320,000 Development of gene therapies for Usher 1F University of Oregon Institute of Neuroscience, Monte Westerfield Lab: $80,000 Testing existing drugs for repurposing for Usher 1F 2025 Grant for year 4 of RUSH1F, 4-year natural history study in partnership with Foundation Fighting Blindness: $200,000. 2026 is year 4 of 4. This study will provide critical data for a future clinical trial. $5000 awarded to Usher Syndroom, Netherlands, for support/sponsorship of international Usher syndrome scientific research conference Total payment to Unravel Biosciences to identify drugs for repurposing for Usher 1F: $45,610 with an additional $45,610 due early 2026 at conclusion of study. Total grants awarded in 2025: $350,610 Key Research advances realized in 2025: Harvard conducting further preclinical testing of mini-gene Harvard team published the following paper in peer-reviewed journal: Mini-Pcdh15b Gene Therapy Rescues Visual Deficits in a Zebrafish Model of Usher Syndrome Type 1F https://www.biorxiv.org/content/10.1101/2025.11.05.686814v1 2 more papers in progress from Harvard lab for publication in 2026 Corey lab is now testing gene therapy from The Salk Institute, Samuel Pfaff lab, and early results are exciting. Hired a consultant to take our mini-gene through the next steps to apply for a clinical trial. Agreement in progress. Will include with 2026 audit since its not yet signed.Expenses $712,836 · grants $696,990
What it must file and when
IRS records say it files Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N. Its accounting year ends in December, so each return is due on the 15th day of the 5th month after that.
| Tax year | Year ended | Due | IRS public records |
|---|---|---|---|
| 2025 | December 31, 2025 | May 15, 2026 | 990 on file |
| 2024 | December 31, 2024 | May 15, 2025 | 990 on file |
| 2023 | December 31, 2023 | May 15, 2024 | 990 on file |
IRS record
- EIN
- 46-4309387
- Tax-exempt status
- 501(c)(3): Charitable, religious, educational or scientific organization
- Foundation status
- Publicly supported organization (170(b)(1)(A)(vi))
- Donations deductible (Pub 78)
- Public charity, 50% deduction limit
- Exempt since
- 2014
- Accounting year ends
- December
- Files
- Form 990 or 990-EZ
- Category (NTEE)
- Medical research (H40)
- Assets (IRS master file)
- $691,312
- Income (IRS master file)
- $826,632
Filing history
| Form | Year ended | Revenue | Expenses | Assets | Return |
|---|---|---|---|---|---|
| 990 | December 2025 | $743,572 | $885,485 | $691,312 | XML |
| 990 | December 2024 | $845,716 | $871,099 | $781,549 | XML |
| 990 | December 2023 | $446,533 | $646,264 | $810,900 | XML |
| 990 | December 2022 | $1,082,978 | $932,832 | $1,300,335 | IRS |
| 990 | December 2021 | – | – | – | IRS |
| 990 | December 2020 | – | – | – | IRS |
| 990 | December 2019 | – | – | – | IRS |
| 990 | December 2018 | – | – | – | IRS |
| 990-N for 2013 Officer: Melissa Chaikof | December 31, 2013 | ≤ $50,000 receipts | – | – | e-Postcard |
990-N: the IRS bulk file holds only the latest e-Postcard per organization; earlier years come from archived copies of that file since 2020 and can have gaps (the IRS e-Postcard search lists every one). 990, 990-EZ, 990-PF, 990-T: every e-filed return in the IRS e-file index since 2019; XML for the latest three processing years, amounts from the IRS Statistics of Income extracts before that. PDF copies and determination letters at the IRS (search EIN 46-4309387).
Questions about USHER 1F COLLABORATIVE INC
- What is the EIN of USHER 1F COLLABORATIVE INC?
- The employer identification number (EIN) of USHER 1F COLLABORATIVE INC is 46-4309387.
- Is USHER 1F COLLABORATIVE INC tax-exempt?
- Yes. The IRS lists it as tax-exempt under section 501(c)(3) since 2014.
- Are donations to USHER 1F COLLABORATIVE INC tax-deductible?
- Yes. It is listed in IRS Publication 78 (Public charity, 50% deduction limit).
- Which annual return does USHER 1F COLLABORATIVE INC file?
- Form 990 or 990-EZ. Based on its last return; a smaller organization may file the 990-N.
- When is the next return of USHER 1F COLLABORATIVE INC due?
- The return for tax year 2026 (the year ending December 31, 2026) is due May 17, 2027. Form 8868 extends it by six months; the 990-N cannot be extended.
- When did USHER 1F COLLABORATIVE INC last file with the IRS?
- The latest return in the IRS public files is the 990 for the year ended December 2025.
- Who is the principal officer of USHER 1F COLLABORATIVE INC?
- The 990 for the year ended December 31, 2025 names Melissa Chaikof.
- Who are the officers and directors of USHER 1F COLLABORATIVE INC?
- The 990 for the year ended December 31, 2025 lists 12 people; 0 received compensation from the organization.
- How much revenue does USHER 1F COLLABORATIVE INC have?
- On its 990 for the year ended December 31, 2025 it reported revenue of $743,572, expenses of $885,485 and total assets of $691,312 at year end.
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